Corning® Matrigel® Matrix High Concentration (HC), Phenol-Red Free *LDEV-Free, 10mL

SKU: DL111

£856.20

{price} OFF

10+ In Stock

Quantity

Guarantee Safe
Checkout

Secure_Checkout_Options_-_Appleton_Woods

Description

Corning extracellular matrices (ECMs) enable researchers to mimic in vivo environments for 2D and 3D cell culture applications.

Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumour rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Unique Features

Proven and trusted since 1985; most extensively referenced basement membrane matrix
Wide selection of basement membranes; used in diverse applications, from cancer and stem cell research to neurobiology
Manufactured under stringent quality control practices that exceed industry standards, ensuring protein consistency and superior product performance
Rigorous validation for functionality
Certified LDEV-free

Applications

Corning Matrigel matrix is effective for the attachment and differentiation of both normal and transformed anchorage-dependent epithelioid and other cell types. These include neurons, Sertoli cells, chick lens, vascular endothelial cells, and hepatocytes.

Influencing gene expression in adult rat hepatocytes
3D culture in mouse and human mammary epithelial cells
In vivo peripheral nerve regeneration
Metabolism and toxicology studies
The development of several types of tumour cell invasion assays
The in vitro and in vivo study of angiogenesis
In vivo propagation of human tumours in immunosuppressed mice
The maintenance of human embryonic stem cells and induced pluripotent stem (hiPS) cells
Neuronal differentiation of hiPS cells

Matrigel Matrix Quality Control Specifications

Mouse colonies routinely screened for pathogens via mouse antibody production (MAP) testing
LDEV-free EHS tumour
Extensive PCR testing performed on a number of pathogens, including LDEV, ensuring strict control of raw materials used during manufacturing
Tested and found negative for the presence of bacteria, fungi, and mycoplasma
Protein concentrations determined by Lowry method
Endotoxin units measured by Limulus Amoebocyte Lysate assay
Gel stability tested for a period of 14 days at 37°C
Biological activity determined for each lot using a neurite outgrowth assay; chick dorsal root ganglia, plated on a 1.0 mm layer of Corning Matrigel matrix, required to generate positive neurite outgrowth response after 48 hours without the addition of nerve growth factor

Request Specific Product Information

If the product info you require is not listed above, our dedicated UK team of lab product experts will be happy to provide what you are looking for.

PRODUCT INFO REQUEST FORM

Delivery

Standard Delivery £15.00 +VAT.

Delivery Schedule All in stock items will be dispatched within 2 working days.

Exemption The standard delivery fee does not apply to certain items. These may be subject to additional shipping charges, for example capital equipment items or dry ice shipments. Please contact our office for details.

Back Orders If your item is not in stock, we will back order it for you. Any in stock items on your order will be part-shipped on our standard delivery schedule at no additional charge. You will always be emailed with the option to cancel your order if you would rather not wait.

Return Policies

All goods supplied by the Company shall be examined and checked immediately upon receipt by the buyer.

The company should be notified in writing within 48 hours of any damages, shortages or errors in the consignment. No claim whatsoever will be accepted by the Company in respect of any damage or shortage after this time. Where there is a total loss of the Goods in transit, the customer must notify the company within seven days of the invoice. If no such notice is given, the Goods shall be deemed to have been supplied in accordance with the order and to have been accepted by the Buyer. Goods that conform to the Buyer’s order may not be returned without the consent of the Seller.

The Seller reserves the right to impose a handling charge of 20% of the net invoice value for returned Goods. The Seller reserves the right to refuse to accept any Goods returned, for whatever reason, if after inspection such Goods or their packaging prove unsatisfactory in any way. The Buyer is responsible for ensuring that any returns are free from biological and chemical hazard. The seller reserves the right to refuse to accept Goods which in its view present a hazard to its staff or which may infringe the Health & Safety at Work legislation.

Related Products

Account Holder Benefits

Rewarding You and Your Lab For Shopping Local

As a UK independent lab supplier, we really appreciate you shopping local with us and supporting the UK science economy. To say thanks, all Appleton Woods account holders receive: